How are weight changes and muscle loss treated?
To help manage
these symptoms, your oncologist may prescribe medicines such as megestrol
acetate (Megace), anti-nausea medications, and steroid medications. These drugs
can increase appetite for some people and may help to prevent weight and muscle
loss, but they do not build up lost muscle tissue. A lot of research is
underway to better help patients with these problems. There are two promising
treatments that are currently in clinical trials. One trial involves ghrelin, a
hormone that affects appetite and stimulates the release of growth hormone to
build strength. Another study involves SARMs (selective androgen receptor
modulators), drugs that encourage the body to build new muscle tissue. An
example is the drug Enobosarm (GTx-024), which is currently being tested in
patients with non-small cell lung cancer. Learn more about these and other
related clinical trials at www.clinicaltrials.gov.
Keep in mind that appetite and energy levels may
be affected by other treatable conditions, such as pain, anxiety or depression.
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